Publications
Research
논문
Trends in the Development of Antibody-Drug Conjugates for Cancer Therapy. Antibodies. 2023.
Improved Separation in Horizontal Protein SDS-PAGE with Double-Deck Flat Electrodes and a Field Inversion Gel Electrophoresis Module. Methods and Protocols. 2023.
Advancements in Bispecific Antibody Development and Research Trends. Microbiology and Biotechnology Letters. 2023.
Antibody Libraries as Platforms to Exploring Target and Receptor Pleiotropy. Israel Journal of Chemistry. 2023.
Agonist (P1) Antibody Converts Stem Cells into Migrating Beta-Like Cells in Pancreatic Islets. Journal of Microbiology and Biotechnology, 2022.
Anti-inflammatory clearance of amyloid-β by a chimeric Gas6 fusion protein. Nature Medicine, 2022.
Antibodies Regulate Dual-Function Enzyme IYD to Induce Functional Synergy between Metabolism and Thermogenesis. International Journal of Molecular Sciences, 2022.
Sestrin2 protects against cholestatic liver injury by inhibiting endoplasmic reticulum stress and NLRP3 inflammasome-mediated pyroptosis. Experimental & Molecular Medicine, 2022.
Spreader‐CDR system for efficient, reproducible, and frugal western blot. Electrophoresis, 2021.
Evaluation of human papillomavirus (HPV) genotyping assays using type-specific HPV L1 reference DNA. Genes & Genomics, 2021.
Nucleic acid nanotechnology for cancer treatment. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, 2020.
4-1BBL regulates the polarization of macrophages, and inhibition of 4-1BBL signaling alleviates imiquimod-induced psoriasis. The Journal of Immunology, 2020.
Agonist antibody converts stem cells into migrating brown adipocyte-like cells in heart. Cells, 2020.
Immunity against cancer cells may promote their proliferation and metastasis. Proceedings of the National Academy of Sciences, 2020.
BRC-mediated RNAi targeting of USE1 inhibits tumor growth in vitro and in vivo. Biomaterials, 2020.
The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation. Scientific Reports, 2019.
USP14 inhibition regulates tumorigenesis by inducing autophagy in lung cancer in vitro. International journal of molecular sciences, 2019.
Early-stage paired housing improves social interaction in neuronal Uba6-deficient mice. Biochemical and biophysical research communications, 2019.
An agonist antibody prefers relapsed AML for induction of cells that kill each other. Scientific Reports, 2019.
Migration-based selections of antibodies that convert bone marrow into trafficking microglia-like cells that reduce brain amyloid β. Proceedings of the National Academy of Sciences, 2018.
An agonist antibody that blocks autoimmunity by inducing anti-inflammatory macrophages. The FASEB Journal, 2016.
Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signaling. Nature communications, 2015.
Antibodies from combinatorial libraries use functional receptor pleiotropism to regulate cell fates. Quarterly Reviews of Biophysics. 2015.
A general method for insertion of functional proteins within proteins via combinatorial selection of permissive junctions. Chemistry & biology, 2015.
Antibodies from combinatorial libraries use functional receptor pleiotropism to regulate cell fates. Quarterly reviews of biophysics, 2015.
Construction of Ovine Customer cDNA Chip and Analysis of Gene Expression Patterns in the Muscle and Fat Tissues of Native Korean Cattle. Journal of Life Science, 2015.
특허
1. 인슐린 분비 베타세포 분화 유도 항체 및 이를 유효성분으로 포함하는 대사성 질환 예방 또는 치료용 조성물 2022년, 국내 특허출원,
10-2022-0116377.
2. 갈색지방세포 분화 유도 항체 및 이를 유효성분으로 포함하는 대사성 질환 예방 또는 치료용 조성물. 국내 특허등록 일자 2021년 1월5일,
등록번호 10-2201368 출원번호 10-2019-0046220
3. Methods and compositions related to In Vivo selection of functional molecules
PCT patent application filed (Aug.18, 2017) PCT/US2017/047585
4. Antibodies for Generating Anti-Inflammatory Macrophage and Related Uses
PCT patent application filed (Sep.12, 2016) PCT/US16/51290
대전광역시 유성구 유성대로 1646 한남대학교 대덕밸리캠퍼스 진리관 720102호
TEL : 042)629-8777(실험실), 042)629-8770(교수 연구실) / FAX : 042)629-8751
E-mail : kyungho1@hnu.kr
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